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About Ketamine

unnamed-1-1024x682 About Ketamine Los Angeles Southern CaliforniaLearn more about Ketamine Infusion Therapy

 Discover how ketamine infusion therapy can relieve chronic pain and depression. Get relief in as little as one treatment!

About Ketamine Infusion Therapy

Ketamine is an anesthetic that has been used on both humans and animals since it was approved by the FDA in 1970. Its ability to anesthetize patients quickly and safely with few side effects was rapidly realized by the medical community. It became a necessity for doctors all over the world because it doesn’t depress patients’ breathing or circulatory systems like other anesthetics. It is also commonly used as a painkiller for this reason, especially for severe injuries and in crisis situations, since slowing respiration and circulation is a major problem with alternatives such as opiates and barbiturate analgesics. It’s also very fast-acting.

“Ketamine is an Essential Medicine” -World Health Organization

Ketamine is one of only two anesthetics listed by the World Health Organization (WHO) as an “essential drug”. The WHO is a specialized agency of the United Nations concerned with international public health. Their essential drugs are “those drugs that satisfy the health care needs of the majority of the population; they should, therefore, be available at all times in adequate amounts and in appropriate dosage forms, at a price the community can afford.” WHO’s essential drugs are the basis for many countries’ national drug policies.

Benefits of Ketamine Infusion Therapy For Depression & Pain

In the last 15 years, ketamine has gradually been used more in non-traditional ways; treating depression and other mood disorders, Complex Regional Pain Syndrome (CRPS/RSD), and other pain conditions. A substantial amount of clinical research on the lifesaving effects of ketamine for mood disorders and ketamine for pain conditions has been conducted by leading institutions all over the world, proving the efficacy of intravenous ketamine treatment for depression for mood and anxiety disorder therapy; regularly reporting around a 70% success rate or higher. Ketamine for suicide prevention has also shown tremendous promise. Yale, Stanford, and New York universities, USC, UCLA, The Cleveland Clinic, The National Institute of Mental Health, Massachusetts General Hospital, Mt. Sinai, and The Black Dog Institute are just a few of the leading institutions that have conducted research proving ketamine’s efficacy.

Multiple Infusions vs. Single Infusion

Much of the early research conducted was based around a single infusion, which proposes two problems. The first one is that many of our patients don’t respond to treatment until after their 2nd or 3rd infusion; some require a full series of six before a benefit is enjoyed. The second problem is that results are generally reported to last an average of 7-10 days with a single infusion. This caused many critics to say, “it works, but it doesn’t last”. Because of this, we pioneered a series of six infusions over 2-3 weeks, producing more pronounced and much longer-lasting ketamine benefits. Since we pioneered this approach, many research papers have been published on this protocol. See our press and research page for some of them. Although ketamine is also sometimes used IM (intramuscularly), subcutaneously, orally, and insufflated as a nasal spray for the treatment of the aforementioned conditions, we do not administer it through any of these methods. We have heard of some benefit from these methods, but have not seen more than a total of five clinical research papers published on them. Furthermore, there are some real concerns as to the safety and level of control needed for continuity of care with them.

Intravenous Ketamine Infusion Therapy

Receiving intravenous ketamine infusion therapy for depression is the only method of administration that has been clinically proven to be effective and thus the only method currently used by Dr. Steven L. Mandel of Ketamine Clinics of Los Angeles. We have maximum control over your rate of infusion, with the ability to titrate up or down accordingly based on your level of comfort and improvement. If there are any undesired side effects, we can lower the rate and rapidly decrease the amount of medicine in your body, since ketamine has a very short half-life. Additionally, we have an IV established and can quickly provide medicine to manage nausea or anxiety that begins working within one minute. If there are any adverse effects, we can stop the infusion all together. Each infusion will be consistent, not necessarily experienced the same, but consistent, as an IV enables us to provide a crucial continuity of care. We will know exactly, down to the microgram, how much medicine you received. We can ensure you receive less or more at your next infusion depending on your response. The medicine is felt very quickly, usually within five minutes of establishing the IV, and dissipates very quickly, usually within 15-20 minutes of completion.

Read News Reports and Clinical Research on the Rapid Anti-Depressant and Pain Relieving Effects of Ketamine Here

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Contact Us

Ketamine Clinics of Los Angeles
6801 Park Terrace, Suite 525
Los Angeles, CA 90045
P: 310-270-0625
F: 310-730-5993
Monday - Friday: 9:00 am - 5:00 pm
Ketamine Clinics of Los Angeles Location

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