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Ketamine Facts

Interesting Facts About Ketamine

Ketamine is an anesthetic that has been used on both humans and animals for over 52 years. Its ability to anesthetize patients quickly and safely, with few side effects, was quickly realized by the medical community; it was approved by the Food and Drug Administration (FDA) in 1970. It rapidly became a necessity to doctors all over the world because it doesn’t depress patients’ breathing or circulatory systems like other anesthetics. It is also commonly used as a pain killer for this reason, especially for severe injuries and in crisis situations, since slowing respiration and circulation is a major problem with alternatives, such as opiates and barbiturate analgesics. It’s also very fast-acting. Ketamine is one of only two anesthetics listed by the World Health Organization (WHO) as an “essential drug”. The WHO is a specialized agency of the United Nations concerned with international public health. Their essential drugs are “those drugs that satisfy the health care needs of the majority of the population; they should therefore be available at all times in adequate amounts and in appropriate dosage forms, at a price the community can afford”. WHO’s essential drugs are the basis for many countries’ national drugs policy.

Benefits of Ketamine Infusion For Depression & Pain

In the last 20 years, Ketamine has gradually been used more in non-traditional ways; treating depression and other mood disorders, Complex Regional Pain Syndrome (CRPS/RSD), and other pain conditions. In the last decade, a great deal of clinical research has been conducted by leading institutions all over the worldproving IV (intravenous) ketamine’s efficacy in the treatment of these conditions; regularly reporting a 70% success rate or higher. Yale University, The National Institute of Mental Health, Massachusetts General Hospital, and The Black Dog Institute are just a few of those institutions. Much of the research that has been conducted has been based around a single infusion, which proposes two problems. The first one is that many of our patients don’t respond to treatment until after their 2nd infusion. The second problem is that results are generally reported to last an average of 10 days. Because of this, we provide a series of 6 infusions, producing a more pronounced and much longer lasting benefit. Ketamine is also used IM (intramuscularly), subcutaneously, orally, and insufflated as a nasal spray for the treatment of the before mentioned conditions. Receiving Ketamine intravenously is the only method of administration that has been clinically proven to be effective and thus the only method currently used by Dr. Steven L. Mandel of Ketamine Clinics of Los Angeles. Some providers prescribe oral ketamine and nasal spray after IV ketamine treatment in an attempt to extend those results. At Ketamine Clinics, we do not use nasal ketamine or oral ketamine because we have seen little evidence that this is effective.


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11645 Wilshire Blvd
Suite #852
Los Angeles, CA 90025
P: 310-270-0625
F: 310-730-5993
Ketamine Clinics of Los Angeles Location