Ketamine Treatment for Depression in Los Angeles

Many people continue to struggle with depression even after trying psychotherapy and antidepressant medications. If you or someone you love is in the grip of ongoing depression, ketamine treatment for mood disorders can help.

Looking for relief from depression? IV Ketamine Infusion Therapy can help.

We offer low-dose ketamine infusions for depression and other mood disorders, typically after patients’ depression has failed to respond to other forms of treatment. Some have tried everything from talking therapy to countless medications, to transcranial magnetic stimulation (TMS) and even electroconvulsive therapy (ECT or shock treatment). Even for these patients who have been labeled as treatment-resistant, IV Ketamine Infusion Therapy provides relief. Although most of our patients fit this description, we also treat patients with ketamine therapy as an early line of defense because it works quickly, effectively, and safely with no long-term side effects.

Different from Antidepressants

Antidepressants can take weeks or even months to reach therapeutic levels in your system and have an effect. Even then, some patients try many medications in endless combinations and doses and still feel no relief from their depression. Ketamine Infusion Therapy for depression works quickly, sometimes in just a few hours, to deliver a significant relief from symptoms. Most patients see substantial relief within 1-2 days of their 2nd infusion.

Ketamine for depression can deliver relief without the unpleasant side effects of antidepressant medications, which can include loss of libido, weight gain, insomnia or sleepiness, nausea, dizziness, fatigue, dry mouth, blurred vision, and suicidal ideation.

When it’s clear antidepressants aren’t working or providing sufficient relief, ketamine treatment for depression may be exactly what you need.

Is Ketamine Right For Me?


How Ketamine Treatment for Mood Disorders Works

Ketamine Clinics of Los Angeles administers ketamine via IV infusion, which is the only route of administration that is scientifically proven to work. A full course of therapy consists of a series of 6 infusions done over 2-3 weeks with each treatment session lasting 50-55 minutes.

When you undergo ketamine therapy for depression, you’re closely monitored by our highly experienced nurses and Dr. Mandel. He is a board-certified anesthesiologist who also has a master’s degree in psychology. We use hospital grade equipment to monitor your pulse, oxygen saturation, blood pressure, and electrocardiogram. You’ll be kept safe, in a comfortable environment. Some patients experience short-term dizziness, nausea, and fatigue, but these sensations usually disappear rapidly. After 50 years of ketamine being administered at much higher doses, and approximately 15 years of research on ketamine for mood disorders, there have been no long-term side effects.

What You Should Know About Ketamine Treatment

Ketamine is recognized as the safest, most widely used anesthetic in the world. It’s approved for many medical uses in human and veterinary medicine and is commonly used with young children.

World renowned institutions have confirmed the efficacy of ketamine infusions for the treatment of mood disorders and various pain conditions. Yale University, Stanford University, Harvard University, UCLA, USC, NYU, the National Institute of Mental Health, the Black Dog Institute of Australia, Cleveland Clinic, and Mt. Sinai Hospital are a few of the leaders

At Ketamine Clinics of Los Angeles, we offer the best possible care in our state-of-the-art facility in the neighborhood of Brentwood in Los Angeles, California. Our highly experienced, trained, and compassionate team consist of providers who have carefully considered the research and results of IV Ketamine Infusion Therapy. Dr. Mandel has personally administered more ketamine infusions than almost all other providers in the United States.

Many insurers will partially reimburse your cost for ketamine treatment for depression, although it may be a small amount. We do not bill insurance. We will provide you with statements with the necessary billing codes for you to file a claim.

What Researchers Say About Ketamine

Since 2004, researchers at leading medical institutions have performed many studies proving ketamine’s ability to significantly relieve depressive symptoms. According to The Washington Post, many experts, such as Thomas Insel (former Director of the National Institute of Mental Health), are calling ketamine “the most significant advancement in mental health in 50 years”

Ketamine has long been used as an anesthetic and an analgesic in surgeries, emergency rooms, and burn centers. More and more doctors are administering ketamine for the treatment of mood disorders as it’s antidepressant effects are becoming more widely recognized. When administered intravenously, ketamine can help patients get rid of feelings of hopelessness and suicidal thoughts. As the treatment gains popularity, it is increasingly important to see a provider who has the knowledge and experience to provide you with a safe, efficacious infusion.

Why You Should Choose Ketamine Clinics of Los Angeles

At Ketamine Clinics of Los Angeles, we provide ketamine therapy for depression in a calm, comforting state-of-the-art facility. Our staff is experienced, knowledgeable, compassionate, and highly-qualified. Your safety and recovery are our top priorities. Dr. Mandel has the ability to tailor the treatment to fit your unique needs. This personalized approach is one reason we have an 83% success rate among our depressed patients.

Get Depression Help Now

Depression can seriously affect your professional life, your personal life, and the people you love most. You owe it to yourself and them to find an effective depression treatment. Fill out our online contact form or call us at 310-270-0625 today to see if ketamine therapy is right for you.


Mother of PTSD and depression patient

I saw my son once again.

Although all the medical treatment Matt has received was valuable in some way, the only time in 16 years I saw the person who is my son once again quietly emerge, was after the ketamine infusions.

Allen C. 34 year old Male, Engineer

My successes have been phenomenal.

I have cut down on my Effexor to 75 Mg per day. I have eliminated lithium from my regiment and haven’t needed ambien for about month now to sleep. My klonopin I’ve reduced to once every other day. The infusions really helped my depression and chronic pain in my neck. My depression has never been better and I am cutting down on my other medications with great success. Thank you, thank you Dr. Mandel!

37 Year Old Woman, Registered Nurse

When I found Ketamine Clinics of Los Angeles,

When I found Ketamine Clinics of Los Angeles, and began to research the treatment, I felt my spirits lift. I felt hope. From the moment I called their office, I knew I was in good hands. As someone who works in healthcare, I couldn’t believe how kind and attentive Dr. Mandel and his entire staff were. I know they really care about me.

Keith W. 60 year old male, Lawyer

My doctor recommended that I try Ketamine

My doctor recommended that I try Ketamine at this time because he considers that there is now enough clinical information to make an informed decision about its effectiveness and side effects, and specifically recommended Dr. Mandel, who even with a glowing recommendation from someone for whom I have tremendous respect vastly exceeded all of my expectations.


Dr. Mandel has truly made my unlivable life, livable again.

Dr. Mandel has truly made my unlivable life, livable again. My ability to get out of bed early and or nearly right as I wake up has significantly improved. I’m able to keep up with my incredibly hectic schedule. My overall mood is high and lethargy is low. My social anxiety is at an all time low, and I haven’t had a panic attack since my first infusion.

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