Ketamine nasal spray for depression has shown promise in helping some depression sufferers get relief. With more than 16 million Americans affected by major depression, utilizing innovative treatments that provide better relief than conventional antidepressants is more essential than ever. Failure to treat depression increases the risk of drug and alcohol dependence and even suicide. Ketamine therapy is a safe and salient treatment option that is now offering hope to millions of patients suffering from treatment-resistant depression.
Nasal Spray (Esketamine) – Does It Work?
Although IV infusions for ketamine are a proven solution to treat the symptoms of major depressive disorder, some researchers are also looking at the impact of Esketamine (a unique nasal ketamine inhaler), which is a component of the general anesthetic Ketamine. One of the studies published in JAMA indicated that ketamine-based nasal spray may help to rapidly improve the symptoms of depression.
However, a large body of existing research has shown favorable results for ketamine infusion therapy to achieve rapid relief from depression symptoms but has not supported similar conclusions when ketamine is administered through other routes, such as intranasal sprays.
Unpredictability of Ketamine Nasal Spray
When intranasal ketamine for depression is administered, it will present hurdles before it can reach the bloodstream. Therefore, the results from an Esketamine therapy session are, at best, unpredictable. When given through the nose, ketamine will have to pass through the mucous membranes first.
Unable to reach the bloodstream, the drug must be suspended evenly and perfectly in a mist. Then the mist must evenly saturate the nostril’s mucous membranes. Further, the spray has to be targeted accurately in order to land at the right spot and not run down the back of the patient’s throat. The delivery has to be gentle enough to not get sneezed back out.
Additionally, the Ketamine Spray will deliver a mist that provides a concentrated dose of the drug over just a few seconds of contact with the nostril’s mucous membranes. It provides only very brief contact with the delicate and vital brain systems, which require adequate time to alter for the better.
In summary, when ketamine is administered through a nasal spray (Esketamine), there are too many uncontrollable variables, whereas intravenous infusions of ketamine are gradual, controlled, and precise, allowing for much more predictable and controllable outcomes. Ketamine Infusion Therapy enables safe and slow exposure of the critical pathways to the drug for the stimulation of neuronal growth as well as re-arborization.
IV infusions of ketamine are the only route of administration where 100 percent of the medicine becomes available to the body and is delivered to the brain – where it needs to be to treat depression symptoms.
Internationally renowned ketamine treatment expert Dr. Steven L. Mandel provides concierge-level ketamine infusion treatments to patients in Los Angeles, Brentwood, Santa Monica, Venice, Beverly Hills, and other neighborhoods and communities in Orange County and other Southern California areas. If you’re searching for “ketamine treatment near me” then visit Ketamine Clinics of Los Angeles, the premier mental health treatment center specializing in intravenous ketamine infusion therapy.
For more information about Ketamine Infusion Therapy treatments for depression, bipolar, anxiety, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), fibromyalgia, pain syndromes and other conditions contact us at the Ketamine Clinics of Los Angeles in Southern California (Orange County) by clicking here or calling 310-270-0625