More than 16 million Americans are affected by major depression every year, and almost a third of them do not find relief from conventional anti-depressants and other traditional treatment approaches. Failure to treat depression also increases the risk of drug and alcohol dependence, and even suicide.
Ketamine Therapy is a safe and salient treatment option that is now offering hope to millions of patients suffering from treatment resistant depression.
Ketamine Clinics of Los Angeles, led by the dignified, astute, and dedicated Dr. Steven L. Mandel, provides Ketamine Infusion Treatments to patients in Los Angeles, Brentwood, Santa Monica, Beverly Hills, Orange County, California and other neighborhoods and communities in this area of Southern California and the southwest in general.
Nasal Spray (Esketamine) – Does it Work?
Although IV infusions for Ketamine are a proven solution to treat the symptoms of a major depressive disorder, some researchers are also looking at the impact of Esketamine (a unique Ketamine Nasal Spray), which is a component of the general anesthetic Ketamine. One of the studies published in JAMA indicated that Ketamine-based Nasal Spray may help to rapidly improve the symptoms of depression.
However, a large body of existing research has shown favorable results for Ketamine Infusion Therapy to achieve rapid relief from depression symptoms, but has not supported similar conclusions when Ketamine is administered through other routes, such as intranasal sprays.
Unpredictability of Ketamine Nasal Spray
When Ketamine is administered through the nasal route, it will present hurdles to the drug before it can reach the blood stream. Therefore, the results from an Esketamine Therapy are, at best, unpredictable. When given through the nose, Ketamine will have to pass through the mucous membranes first.
Unable to reach the blood stream, the drug must be suspended evenly and perfectly in a mist. Then the mist must evenly saturate the nostril’s mucous membranes. Further, the spray has been targeted accurately in order to land at the right spot and not run down the back of the patient’s throat. The delivery has to be gentle enough to not get sneezed back out.
Additionally, the Ketamine Spray will deliver a mist that provides a concentrated dose of the drug over just a few seconds of contact with the nostril’s mucous membranes. It provides only very brief contact with the delicate and vital brain systems, which require adequate time to alter for the better.
In summary, when Ketamine is administered through a Nasal Spray (esketamine), there are too many if’s and but’s involved, whereas, intravenous Infusions of Ketamine are gradual, controlled and precise, allowing for much more predictable and controllable outcomes. Ketamine Infusion Therapy enables safe and slow exposure of the critical pathways to the drug for the stimulation of neuronal growth as well as rearborization.
IV infusions of Ketamine are the only possible route where 100 percent of the administered drug becomes available to the body and delivered 100 percent to the brain – where it needs to be to treat depression symptoms.
Accomplished and honorable Ketamine specialist Dr. Steven L. Mandel provides excellent Ketamine Infusion Treatments to patients in Los Angeles, Brentwood, Santa Monica, Beverly Hills, Orange County, California and other neighborhoods and communities in this region of Southern California and the southwest in general.
For more information about Ketamine Infusion Therapy treatments for depression, bipolar, anxiety, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), fibromyalgia, pain syndromes and other conditions contact us at the Ketamine Clinics of Los Angeles in Southern California (Orange County) by clicking here or calling 310-270-0625