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Sam Mandel, COO

Chief Operating Officer

unnamed-1024x819 Sam Mandel, COO Los Angeles Southern CaliforniaSam Mandel is an entrepreneur and actor who has achieved significant success in both business and entertainment.  His worldwide travel as a child launched him on a journey which today includes serving as Chief Operating Officer at Ketamine Clinics of Los Angeles as well as performing in film and television.

Born and raised in Los Angeles, California, Sam spent his grammar school years sailing the world on a 71-foot yacht with his mom, dad, and older twin sisters. They explored countless islands in the Bahamas, Caribbean, and British Virgin Islands. Sam was homeschooled by his father while his sisters were taught by their mother. Counting mangos for math class and snorkeling for recess, Sam would later discover his early years in school were very different from his peers. This early exposure to other cultures and nontraditional thinking formed the basis for much of his professional life.

As a child, he was empowered with possibility and recognized he wasn’t limited to just one vocation or avocation. He knew he loved to entertain. Inherently he understood the healing power of laughter. By age 9, he was acting professionally in film, TV, and commercials; including starring roles on ABC and Disney shows, as well as national commercials.

Unlike most of his friends and fellow actors, Sam also had a strong interest in business. His father’s side of the family has been heavily involved in New York City real estate for over a century while his mother’s side is entrepreneurial. By age 10, Sam created his first business. He ordered business cards and delivered them to his neighbors’ mailboxes offering his dog walking services. Before long, he was dog sitting and dog walking often enough to involve friends in his endeavor so he could still go to class and auditions.

At age 13, Sam volunteered at Teen Line, a non-profit teen-to-teen support and suicide hotline where he took calls from struggling teens, providing counseling and resources. This sparked Sam’s work in mental health. He was driven to learn more in this field of work as he was exposed to the struggles of friends and family. Throughout his teen years, he volunteered for numerous non-profits including building homes with Habitat for Humanity and raising funds for veterans and other underserved communities to have access to better healthcare.

Since then, Sam has held a variety of positions in many different industries including finance, retail, hospitality, real estate, and entertainment. With such an eclectic mix of work experience, Sam brings a unique perspective to his father’s field of medicine.

In 2014, Sam took on his most challenging role yet; co-founding and operating Ketamine Clinics of Los Angeles, which he started with his father Dr. Steven L. Mandel. The two opened the clinic out of a desire to offer an innovative solution to those suffering from mood disorders and chronic pain. Since then, their clinic has become the premiere clinic offering Ketamine Infusion Therapy in the world. Sam brings excellent service and compassion to patients that are in emotional and physical pain. Drawing from the best principles in multiple industries, Sam strives to ensure that everyone associated with the clinic give each patient the attention once reserved for only the uber wealthy, reminiscent of the doctor-patient relationship of decades gone by. This focus has translated to the highest level of patient satisfaction. Sam accomplished this success through building a team environment founded on integrity and respect.

Sam and his entire team at Ketamine Clinics of Los Angeles live by the clinic’s mission of high-quality, personalized, compassionate care and their 5-star rating on Yelp and other social networks reflects this.

Always an entertainer, Sam puts patients at ease through laughter and believes it is an important part of their treatment. When not in-clinic, Sam can be found acting and directing in a variety of projects. A SAG-AFTRA actor with over 40 principal credits in Film, TV, commercials, voiceovers, and theatre, Sam loves to inspire and entertain.

Visit for more information on Ketamine Infusion Therapy and for more information on Sam’s entertainment career.

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Ketamine Clinics of Los Angeles
11645 Wilshire Blvd., Suite 852
Los Angeles, CA 90025
P: 310-270-0625
F: 310-730-5993
Monday - Friday: 9:00 am - 5:00 pm
Ketamine Clinics of Los Angeles Location