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Ketamine used to manage opioid / Pain killer medicine withdrawals

Tag Archives: Chronic Pain Treatment

The Ongoing Challenge of Chronic Pain, Opioid Addiction, and Opioid Withdrawal

Ketamine-used-to-manage-opioid-Pain-killer-medicine-withdrawals-300x200 Ketamine used to manage opioid / Pain killer medicine withdrawals Los Angeles Southern CaliforniaFor individuals whose lives have been turned upside down by persistent, long-term chronic pain, the options offered by today’s modern medical science can seem almost miraculous. In the late 1990s, pharmaceutical companies practically promised to make chronic pain a thing of the past with the introduction of powerful prescription pain medications such as oxycodone and hydrocodone. These synthetically-derived medications are known as “opioids” because they have the same chemical structure as drugs like morphine and heroin that are naturally derived from the poppy plant.

Now, more than two decades later, we have come to realize that the promise of opioid pain medications comes with a very dark side. While these medications do offer significant pain relief, they also carry the very real risk of serious, long-term addiction and the potential for overdose. According to a 2015 article in Pain magazine, it is estimated that between 21 and 29% of patients who are prescribed opioids for chronic pain misuse them.[1] According to the National Institute of Drug Abuse, it is estimated that 2 million people in the United States suffer from addiction relating to prescription opioid pain relievers, while more than 33,000 Americans died of an opioid overdose in 2015 alone.[2]

Of course we know that most individuals taking opioids for chronic pain don’t want to become addicted: they simply want to live their lives free of pain. Unfortunately, when opioids are taken over the long term, the brain naturally builds up a tolerance or resistance to the drug, so the patient must take it in higher and higher dosages to achieve the same pain relieving effects. Conversely, reducing or eliminating the brain’s growing dependence on the opioid not only brings back the chronic pain in full force, but can also bring with it very serious physical withdrawal symptoms that themselves require additional medications.

Ketamine as a Potential Solution to Opioid Withdrawal and Chronic Pain

Now, it appears that science has once again come through with a solution to this growing problem in the form of Ketamine Infusion Therapy. Ketamine Therapy involves delivering ketamine, a well-known anesthetic, directly into the blood stream in sub-anesthetic doses. Although scientists are still in the process of understanding the complex ways in which ketamine, as an NMDA receptor antagonist, alters the chemistry of the brain, both recent studies and anecdotal evidence strongly suggest that ketamine can play a powerful and positive role in combatting opioid withdrawal and managing chronic pain.

Specifically, IV Ketamine Infusion Therapy may be able to break the dangerous cycle of opioid pain medications in several important ways:

  1. Ketamine Therapy can address immediate withdrawal symptoms that may result from a rapid reduction in opioid usage. Ketamine has proven effective in treating both the physical symptoms of withdrawal, such as nausea, vomiting, abdominal cramping, diarrhea, and restlessness, and the emotional side effects, most critically depression, which is one of the leading causes of relapse back into opioid addiction.
  1. IV Ketamine Infusion Therapy can help reduce tolerance (drug resistance) to opioid medications. In other words, by enabling the patient to eliminate the use of opioids for a period of time, the patient reverses the built-up tolerance and effectively returns to a state of being “opioid naïve”. This means that should it become necessary to return to the use of opioids to manage chronic pain, the patient will require significantly lower dosages of the medication.
  1. IV Ketamine Infusion Therapy may offer—for some patients—an alternative method of pain relief. By offering an alternative treatment for pain medication, one which does not appear to have the same long term side effects or significant risk of addiction (when used properly through a qualified medical practitioner), ketamine may eliminate the need for opioid medications entirely. This alternative is especially important for patients who have a past history of addiction or for whom opioid medications are simply not appropriate.

It is important to note that ketamine itself is a powerful drug with a long history of abuse as a popular street drug. IV Ketamine Infusion Therapy is a precise medical treatment in which ketamine is administered very slowly and in very small doses, in a medically-appropriate controlled setting supervised by physicians and highly-qualified medical personnel. Using ketamine to fight opioid addiction without proper medical supervision can be dangerous. It is absolutely critical that anyone facing opioid addiction should seek professional and/or medical help to cope with the addiction, rather than attempting another form of self-medication.

 

Contact Ketamine Clinics of Los Angeles

If you or someone you love is suffering from an addiction to an opioid, we encourage you to contact Dr. Steven L. Mandel at Ketamine Clinics of Los Angeles immediately to find out if IV Ketamine Infusion Therapy may offer a solution.

For more information about Ketamine Infusion Therapy treatments for depression, bipolar, anxiety, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), fibromyalgia, pain syndromes and other conditions contact us at Ketamine Clinics of Los Angeles in Southern California (Orange County) by clicking here or calling  310-270-0625.

 

[1] Pain. 2015 Apr;156(4):569-76.

[2] https://www.drugabuse.gov/drugs-abuse/opioids/opioid-overdose-crisis#five

Chronic Pain Treatment

Clinical-Pain-Advisor-793x630 Experts Create Guidelines for the Use of Ketamine for Chronic Pain Los Angeles Southern CaliforniaPhysicians treating patients suffering from neuropathic chronic pain conditions, such as  fibromyalgia, chronic regional pain syndrome (CRPS), and chronic migraines now have guidelines to follow when using intravenous ketamine infusions. Experts from the Ketamine Guidelines Committee which includes representatives from the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists, have published guidelines for physicians in Regional Anesthesia and Pain Medicine.

The guidelines covered several instructions for administering and monitoring treatment, and how to determine whether IV Ketamine Infusion Therapy has a positive response in chronic pain patients. Overall, the consensus was that there is enough evidence in support of the use of Ketamine Therapy for treating chronic pain, but the quality of evidence available does differ between conditions and dosage.

The Link Between Ketamine Therapy and Pain Management

IV Ketamine Infusion Therapy has slowly gained recognition in the medical and scientific community as a viable option for managing chronic pain symptoms. Ketamine has been used for decades as an anesthetic and is also commonly an abused ‘recreational drug’ because of its tranquilizing and sedative effects. However, when administered at a certain dosage, ketamine can help relieve much of the pain and discomfort chronic pain sufferers deal with on a daily basis.

Research on Ketamine for Chronic Pain

An article published in Anesthesia, Essays and Researches in 2014 reports on newly found anti-inflammatory properties of ketamine and the effects of IV low dose ketamine for acute pain management. Some reports even indicate that ketamine plays a role in preventing postoperative chronic pain. For patients suffering from non-cancer chronic pain, ketamine can be used off-label to treat many chronic painful conditions, according to the report.

Unlike prescription drugs that can cause adverse side effects, Ketamine Therapy has no known side effects. It is easy to administer and well tolerated by many. Still, the panel of experts report that it IV Ketamine Infusion Therapy does need to be monitored when administered in very high doses or at a higher frequency. When administered at low doses and carefully monitored, ketamine can provide numerous benefits for pain sufferers seeking ongoing pain relief.

Now, physicians have medical guidelines from the Ketamine Guidelines Committee to follow. These include recommendations on using IV Ketamine Infusion Therapy when patients are undergoing painful surgery and also for patients who are considered to be opioid-dependent or opioid-tolerant. Even patients with sleep apnea who would otherwise turn to opioids can be good candidates for Ketamine Therapy. The committee concluded that, “ketamine remains a powerful tool for practitioners who manage acute pain.”

More research is underway to study the effects of ketamine on chronic pain. Ketamine therapy might be a viable option for pain sufferers when administered in conjunction with opioids and adjuvants, according to the latest guidelines.

Read more on ClinicalPainAdvisor.com

For more information about Ketamine Infusion Therapy treatments for depression, bipolar, anxiety, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), fibromyalgia, pain syndromes and other conditions contact us at Ketamine Clinics of Los Angeles in Southern California (Orange County) by clicking here or calling  310-270-0625.

Pain Treatment with Ketamine

shutterstock_96023894 Ketamine IV Therapy Can Help With Pain Syndromes Los Angeles Southern CaliforniaMost people will experience mild or severe form of pain due to some reason during their lifetime. Persistent or severe pain can debilitate a person and hamper their performance of normal activities. When such pain becomes chronic, it can have a crippling effect on their quality of life.

The patient will struggle with their work and household duties, and find it difficult to concentrate at anything due to continuing pain. Chronic pain can happen due to many reasons, and often it can be difficult to manage this pain for a long time with conventional pain medications and anti-inflammatory drugs.

Many patients suffering from pain syndromes resort to seeking relief with muscle relaxants, steroids and opiates. These can become addictive and carry unpleasant side effects. Amid widespread problem of pain syndromes, Ketamine Infusion Therapy has emerged as a credible solution for many patients.

Ketamine IV treatment has proved to be safer and more efficacious, while providing faster relief from the symptoms. Ketamine Therapy also avoids the unpleasant side effects typically associated with conventional pain medications. The patient can comfortably receive ketamine infusions in an office setting under the supervision of a qualified ketamine provider.

With low dose, controlled treatment program with ketamine, patients can achieve sustainable relief from chronic pain conditions. The astute Dr. Steven L Mandel is an experienced anesthesiologist providing ketamine infusion treatments to patients in Los Angeles, Beverly Hills, Orange County, California, and surrounding communities.

Ketamine Advantage

One of the problems with chronic physical pain is that it can acquire a psychological dimension over time, and in some cases, may lead to the onset of depression. Ketamine Therapy offers a unique advantage in this situation by treating both physical pain and the symptoms of depression at the same time. T

A key property of ketamine is that it can block and reset pain receptors in the brain and balance out neurons and hormones by altering glutamate and GABA levels. As the ketamine specialist delivers Ketamine Infusion Therapy in controlled low level dosages, it can simultaneously address physical as well as psychological discomfort being caused by chronic pain.

Pain Syndrome Management with Ketamine

Complex Regional Pain Syndrome (CRPS), also known as Reflex Sympathetic Dystrophy (RSD), is a chronic pain condition that may worsen if left untreated. The pain first occurs in the leg or arm in most cases, and gradually spreads to other areas. CRPS is a severely painful condition with a score of 42 out of 50 on the McGill pain scale.

The increase in the number of NMDA receptors cause intensifying of the pain because the pain signals are amplified. This is where Ketamine Therapy can be highly effective because it will interfere with the NMDA receptors. Ketamine will naturally block and reset the pain signal process, and provide relief from pain in a situation where other treatments have failed to work.

NMDA receptor blockage stops the pain from reaching the brain and the spinal cord. The central pain centers are consequently rebooted and get desensitized to peripheral pain signals. Dr. Mandel receives patients from Los Angeles, Beverly Hills, Orange County, California, and nearby areas for ketamine infusion treatments.

For more information about Ketamine Infusion Therapy treatments for depression, bipolar, anxiety, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), fibromyalgia, pain syndromes and other conditions contact us at the Ketamine Clinics of Los Angeles in Southern California (Orange County) by clicking here or calling  310-270-0625 

Treating patients from Los Angeles, Beverly Hills, Orange County, San Diego, Palm Springs, San Francisco, Sacramento, CA,  Northern & Southern California, Las Vegas, NV and many other cities from west to east coast.

Ketamine For Chronic Pain

Ad-2-300x157 Ketamine For Chronic Pain: Risks And Benefits Los Angeles Southern CaliforniaKetamine, which has been used as an anesthetic for decades by medical professionals, is now increasingly seen as having multiple therapeutic benefits. One of the key benefits of Ketamine Infusion Therapy is its ability to treat the symptoms of several types of chronic pain syndromes, particularly the ones that have a neuropathic component.

During the initial consultation, the Ketamine Therapy provider will discuss the benefits and limitations of this treatment. The Ketamine Clinics of Los Angeles, led by the perspicacious and fabulous Dr. Steven L Mandel, provides ketamine infusion treatments for chronic pain to patients in Los Angeles, Beverly Hills, Orange County, California, and towns and cities in this part the nation.

Benefits

When Ketamine Infusion Therapy is administered in low doses, it can produce strong analgesia in neuropathic pain states. This possibly occurs due to the ability of ketamine to inhibit the N-methyl-D-aspartate receptor. A few other mechanisms may also be possibly involved, including enhancement of descending inhibition and anti-inflammatory effects at central pain sites.

Existing research based evidence about the benefits of short term infusions of ketamine indicates that Ketamine Therapy creates potent analgesia during administration. Additional studies regarding the potential effect of prolonged infusion (4 to 14 days) show long term analgesic effects up to three months following Ketamine Infusion Therapy.

Ketamine is already a proven application for anesthesia and pain management. It can significantly improve post-operative and post-trauma pain scores and reduces opioid consumption.

Risks

The potential risks and side effects of Ketamine Therapy can be mitigated when the treatment is performed by a specialist in a controlled medical environment, and the administration is done via IV in very low doses. The risks of ketamine noted in clinical studies include psychedelic symptoms, such as hallucinations, memory loss, panic attacks, nausea or vomiting, somnolence, cardiovascular stimulation and, in very rare cases, hepatoxicity.

One of the risks that have emerged in recent years is the recreational use of ketamine. Patients who become addicted to ketamine and take it for recreational purposes may face a variety of additional risks ranging from bladder and renal complications to persistent psychotypical behaviour and memory issues.

Minimal Risk for Clinical Patients

The good news is that the risks of ketamine are primarily confined to the ketamine abusers, while clinical patients are largely free of the inherent risks. Therefore, it is not appropriate to blindly extrapolate these potential risks to clinical patients. In clinical settings, Ketamine Infusion Therapy is well tolerated, particularly when benzodiazepines are used to tame the psychotropic side effects.

In any case, for patient safety, even among clinical patients, it is important to closely monitor those receiving, particularly for CNS, haemodynamic, renal and hepatic symptoms as well as abuse. Research is still continuing to determine the precise risk-benefit analysis of Ketamine Therapy, but as of now ketamine is increasingly accepted as a treatment of choice for patients with therapy-resistant severe neuropathic pain.

The Ketamine Clincis of Los Angeles, led by profound and tremendous ketamine specialist Dr. Mandel, receives patients from Los Angeles, Beverly Hills, Orange County, California, and neighborhoods and cities in this section of the state for ketamine infusion treatments.

For more information about Ketamine Infusion Therapy treatments for depression, bipolar, anxiety, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), fibromyalgia, pain syndromes and other conditions contact us at the Ketamine Clinics of Los Angeles in Southern California (Orange County) by clicking here or calling  310-270-0625 

Treating patients from Los Angeles, Beverly Hills, Orange County, San Diego, Palm Springs, San Francisco, Sacramento, CA,  Northern & Southern California, Las Vegas, NV and many other cities from west to east coast.

Chronic Pain Treatment

blog-2-pic Ketamine Infusion for Chronic Pain Los Angeles Southern CaliforniaChronic pain can compromise the quality of life of a patient, and restrict their activities. A number of underlying causes and ailments may contribute to the development of chronic pain. If the condition is mild, it may be possible to manage the pain with physical therapy, diet, exercise and taking anti-inflammatories such as Ibuprofen.

However, in a large number of cases, superficial efforts may not suffice to address chronic pain or help the patient cope with it. Several prescription pain medications, muscle relaxers, opiates, and steroids come with their own side effects and may be addictive. Against these options, Ketamine infusion treatments may prove to be a more effective and safer alternative.

Dr. Mandell Discusses Ketamine Infusion Therapy for Pain Treatment

Multiple infusions of ketamine received intravenously under the guidance of an experienced treatment provider can produce longer lasting and more sustainable relief from chronic pain. Dedicated anesthesiologist Dr. Steven L Mandel, founder of Ketamine Clinics of Los Angeles, provides ketamine IV treatments to patients in Los Angeles, Beverly Hills, California, and surrounding locations.

Efficacy of Ketamine for Chronic Pain

Chronic pain can develop a psychological dimension over time, and may even trigger the onset of depression. In these conditions, a more ideal treatment for chronic pain could be IV ketamine infusion therapy, which will address both physical pain and the symptoms of depression.

Ketamine infusion treatments are designed to block and reset pain receptors in the brain and balance out key neurons and hormones by altering glutamate and GABA levels. This enables a simultaneous treatment of physical as well as psychological discomfort caused due to chronic pain. To make the ketamine therapy more effective, an experienced provider will customize the care plan to fit the patient’s specific needs.

What is CRPS/RSD?

Complex Regional Pain Syndrome (CRPS), also known as Reflex Sympathetic Dystrophy (RSD), is a severe chronic pain condition that is continuous and worsens over time. This condition typically affects a leg or an arm at first, and gradually extends through other parts of the body. Nine in 10 patients report a spreading of the pain and one in three patients experience symptoms throughout the body.

The complexity and inadequate clinical awareness about this pain makes the current treatments very limited in scope and largely ineffective. CRPS is considered the most painful, long term chronic pain condition with a score of 42 out of a possible 50 on the McGill pain scale, making it worse than events such as amputation and childbirth.

Relief from CRPS/RSD

In case of CRPS/RSD, a process called central sensitization is known to intensify pain by increasing the number of NMDA receptors, which amplify the pain signal. Ketamine infusion therapy will interfere with the NMDA receptor and help to block and reset the pain signaling, delivering relief where other treatments have failed.

When NMDA receptors of peripheral nerves are blocked, the transmission of peripheral nerve pain is intercepted before it reaches the spinal cord and brain. This allows for rebooting of central pain centers and desensitization to peripheral pain signals. Dr. Mandel receives patients from Los Angeles, Beverly Hills, and other cities in Southern California for Ketamine infusion treatments.

For more information about treatments for depression, bipolar, anxiety, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), fibromyalgia, pain syndromes and other conditions contact us at the Ketamine Clinics of Los Angeles in Southern California (Orange County) by clicking here or calling  310-270-0625

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Ketamine Clinics of Los Angeles
6801 Park Terrace, Suite 525
Los Angeles, CA 90045
P: 310-270-0625
F: 310-730-5993
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