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New Study Indicates Ketamine Therapy Could Hold Promise for Adolescents Suffering from Depression

Tag Archives: Depression Treatment

Adolescent Depression Treatment

Adolescent-Depression-Treatment-with-Ketamine New Study Indicates Ketamine Therapy Could Hold Promise for Adolescents Suffering from Depression Los Angeles Southern CaliforniaA new study recently published in the Journal of Child and Adolescent Psychopharmacology indicates that ketamine could be a promising treatment option for adolescents suffering from treatment-resistant depression.[1]

The study, conducted by researchers at the University of Minnesota and the Mayo Clinic, followed 13 adolescents aged 12 through 18 who failed to respond positively to two previous trials with traditional antidepressants. Over the course of two weeks, the teens were given six low-dose infusions of ketamine. Researchers found that the IV Ketamine Infusion Therapy resulted in an average decrease of 42% on the Children’s Depression Rating Scale (a widely-used clinical scale for assessing severity of depression and change in symptoms in adolescents) and reported that the treatment was “well-tolerated”.

The authors of the study conclude that these promising results indicate that Ketamine Therapy could provide an alternate treatment for teens and adolescents who have not responded to traditional treatment with antidepressants. This research builds on the growing body of scientific literature supporting low-dose ketamine infusions as a potential treatment for adults with depression, anxiety, PTSD, and other mood disorders.

Successfully Treating Depression in Adolescents is Vital for Long-Term Health

Adolescence is a crucial period of emotional development, and unfortunately for many teens, a time in which depression can begin to manifest. Yet it is also an important period of brain development. If depression is left untreated during this crucial period of development, it can hinder the brain from achieving critical developmental milestones, potentially setting up the potential for long-term negative outcomes such as chronic depression, disability, and even—in the worst cases—suicide. Therefore, many psychiatrists stress the importance of treating depressing quickly and effectively in order to restore healthy brain development during this critical time.

Traditional treatment for depression in teens generally focuses on a combination of therapy/counseling and antidepressants. Unfortunately, antidepressants present several challenges for patients in this age group. First, they take several weeks, if not months, to take effect. This delay can leave teens vulnerable to additional suffering and at a higher risk of suicide. Second, about 40% of adolescents do not respond to the first attempt at intervention with antidepressants, and of those non-responders, only about half respond to the second attempt at treatment. These bleak statistics indicate that among adolescents, a significant number are coping with treatment-resistant depression. Third, antidepressants carry an FDA “black box warning” about the potential for elevated risk of suicidal ideation and behavior in some individuals under the age of 25.

Because ketamine works on the brain differently than antidepressants, it potentially offers a more positive outcome for adolescents who have not responded to treatment with antidepressants or who would like an alternative form of treatment. IV Ketamine Infusion Therapy involves delivering a very low (sub-anesthetic) dose of ketamine slowly into the bloodstream directly via an IV. Many patients who have undergone Ketamine Therapy report feeling an immediate sensation of relief and a rapid easing of depressive symptoms. The duration of these results is unique to each patient.

Contact Ketamine Clinics of Los Angeles

If your child or adolescent is struggling with depression or has not responded to treatment with antidepressants, we encourage you to contact Dr. Steven L. Mandel at Ketamine Clinics of Los Angeles immediately to find out if IV Ketamine Infusion Therapy may offer a solution.

For more information about Ketamine Infusion Therapy treatments for depression, bipolar, anxiety, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), fibromyalgia, pain syndromes and other conditions contact us at Ketamine Clinics of Los Angeles in Southern California (Orange County) by clicking here or calling  310-270-0625.


[1] Journal of Child and Adolescent Psychopharmacology VOL. 28, NO. 7

Intravenous Ketamine for Adolescents with Treatment-Resistant Depression: An Open-Label Study

Kathryn R. Cullen, Palistha Amatya, Mark G. Roback, Christina Sophia Albott, Melinda Westlund Schreiner, Yanan Ren, Lynn E. Eberly, Patricia Carstedt, Ali Samikoglu, Meredith Gunlicks-Stoessel, Kristina Reigstad, Nathan Horek, Susannah Tye, Kelvin O. Lim, and Bonnie Klimes-Dougan.

Published Online: 14 Sep 2018 (

Ketamine-cure-for-depression--1289x630 CBS News Reports: Is ketamine the cure for depression? Los Angeles Southern CaliforniaLisa Newman has battled depression for more than 30 years. She says she’s finally finding relief with ketamine infusions.

“It’s completely changed my life,” she said. “I’ve cut my antidepressants in half, which I never thought that I would do.”

Ketamine is a powerful anesthetic and pain reliever, known as the party drug “Special K.” Now, the drug is gaining popularity to treat severe depression symptoms.

Dr. Steven Mandel runs ketamine clinics of Los Angeles. Patients receive small doses of ketamine through infusions. He says while antidepressants take several weeks to work, ketamine kicks in within hours and the effects last up to three months.

“Many of them have tried every drug you’ve heard of, some you haven’t. And these people come to me because they haven’t been relieved by any of these things.” Mandel said.

Read more

Watch the video on CBS NEWS Click Here

Behind the Scenes Video


For more information about treatments for depression, bipolar, anxiety, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), fibromyalgia, pain syndromes and other conditions contact us at the Ketamine Clinics of Los Angeles in Southern California (Orange County) by clicking here or calling  310-270-0625 

Treating patients from LA, Beverly Hills, Orange County, San Diego, Palm Springs, San Francisco, Sacramento,CA,  Las Vegas, NV and many other cities from west to east coast.

Depression Treatment

Blog-Post-3 Ketamine Infusion IV Therapy to Treat Depression Los Angeles Southern CaliforniaDepression is a widespread problem in today’s world, with many patients continuing with their struggle against it even after receiving psychotherapy and antidepressant drugs. Ketamine infusion treatments may be able to treat depression and mood disorders in many patients more effectively than the traditional alternatives.

Ketamine Clinics of Los Angeles, led by experienced anesthesiologist Dr. Steven L Mandel, provides advanced ketamine IV therapy to address depression. The customized treatment approach adopted by Dr. Mandel allows him to have a success rate as high as 83 percent among his patients suffering from depression. He provides ketamine infusion treatments to patients in Los Angeles and Beverly Hills and surrounding locations.

Successful Outcomes

Dr. Mandel and his team will offer tailor-made low-dose ketamine IV infusions to treat depression and other mood disorders, typically after the condition has failed to respond to other forms of treatment. Even for a patient who has tried multiple treatments previously and has been labeled as treatment resistant, IV ketamine infusion treatments can yield successful results.

While a majority of patients who seek this therapy from Dr. Mandel have experienced little success with traditional treatments, some others may also gain relief from depression when they receive ketamine therapy as an early line of defense. When delivered in a controlled manner in a state of the art treatment environment, Ketamine therapy will work safely, quickly and effectively with no long term side effects.

Superiority over Antidepressants

Conventional antidepressants can take several weeks or even months to become effective and reach therapeutic levels in the body. Even then, many patients fail to find adequate relief from their depression. On the other hand, Ketamine infusion treatments for depression work fast, sometimes in just a few hours, to deliver marked relief from symptoms. Most patients experience considerable relief within one or two days of their second infusion.

Another advantage is that ketamine for depression can provide relief without the undesirable side effects of conventional antidepressants, which may include weight gain, insomnia, loss of libido, sleepiness, dizziness, nausea, fatigue, blurred vision, dry mouth and suicidal ideation. Once it is apparent that antidepressants are not working, the patient should consider ketamine therapy for superior relief.

How does it Work?

At Kemaine Clinics of Los Angeles, Dr. Mandel and his staff will work closely with the patient to determine a customized ketamine IV therapy plan to address mood disorders. They will administer ketamine via IV infusion because it is only scientifically proven route of administration that works. The full treatment course will include a series of six infusions delivered over two weeks. A single treatment session will last for less than one hour.

During the ketamine therapy for depression, the patient’s condition will be closely monitored by board certified anesthesiologist Dr. Mandel and his team. Hospital grade equipment will be employed to monitor the patient’s pulse, blood pressure, ECG, and oxygen saturation.

Mild short-term side effects such as dizziness, fatigue and nausea may occur, but will dissipate quickly. Dr. Mandel receives patients from Los Angeles, Beverly Hills, and nearby areas for IV ketamine infusion treatments.

For more information about treatments for depression, bipolar, anxiety, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), fibromyalgia, pain syndromes and other conditions contact us at the Ketamine Clinics of Los Angeles in Southern California (Orange County) by clicking here or calling  310-270-0625

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Ketamine Clinics of Los Angeles
6801 Park Terrace, Suite 525
Los Angeles, CA 90045
P: 310-270-0625
F: 310-730-5993
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